I do check the Index Advisor on a regular basis to see what is recommended. I have found that this perspective can become overwhelmed by old data. Who cares what index were advised over a year ago? I either addressed that advice, or the program(s) were changed that used the files in that way.
Every six months I go into the tool and clear the data. This way I will only see the recent recommendations. I have an entry in my calendar to remind me to do this. Wouldn't it be nice if this could be automated.
As part of the latest Technology Refreshes, IBM i 7.6 TR1 and 7.5 TR7 a new Global variable is introduced that will automate the purging for me.



